Only in Titles

           Search results for: Rat Anti-Mouse CDw199   

paperclip

#23939174   // Save this To Up

[Neutralization of interleukin-17 aggravates respiratory infection induced by Chlamydia trachomatis in mice].

To evaluate the role of interleukin-17 (IL-17) in respiratory infection with Chlamydia trachomatis in mice.

1325 related Products with: [Neutralization of interleukin-17 aggravates respiratory infection induced by Chlamydia trachomatis in mice].

Human Interleukin-17E (IL Human Interleukin-17F IL- Human Interleukin-17AF He Human Interleukin-17A IL- Mouse Interleukin-17A IL- Mouse Interleukin-17E (IL Mouse Interleukin-17AF He Mouse Interleukin-17F IL- interleukin 17 receptor C Recombinant Human Interle Recombinant Human Interle Recombinant Human Interle

Related Pathways

paperclip

#21702044   // Save this To Up

Humoral response to catumaxomab correlates with clinical outcome: results of the pivotal phase II/III study in patients with malignant ascites.

The trifunctional antibody catumaxomab is a targeted immunotherapy for the intraperitoneal treatment of malignant ascites. In a Phase II/III trial in cancer patients (n = 258) with malignant ascites, catumaxomab showed a clear clinical benefit vs. paracentesis and had an acceptable safety profile. Human antimouse antibodies (HAMAs), which could be associated with beneficial humoral effects and prolonged survival, may develop against catumaxomab as it is a mouse/rat antibody. This post hoc analysis investigated whether there was a correlation between the detection of HAMAs 8 days after the fourth catumaxomab infusion and clinical outcome. HAMA-positive and HAMA-negative patients in the catumaxomab group and patients in the control group were analyzed separately for all three clinical outcome measures (puncture-free survival, time to next puncture and overall survival) and compared to each other. There was a strong correlation between humoral response and clinical outcome: patients who developed HAMAs after catumaxomab showed significant improvement in all three clinical outcome measures vs. HAMA-negative patients. In the overall population in HAMA-positive vs. HAMA-negative patients, median puncture-free survival was 64 vs. 27 days (p < 0.0001; HR 0.330), median time to next therapeutic puncture was 104 vs. 46 days (p = 0.0002; HR 0.307) and median overall survival was 129 vs. 64 days (p = 0.0003; HR 0.433). Similar differences between HAMA-positive and HAMA-negative patients were seen in the ovarian, nonovarian and gastric cancer subgroups. In conclusion, HAMA development may be a biomarker for catumaxomab response and patients who developed HAMAs sooner derived greater benefit from catumaxomab treatment.

1076 related Products with: Humoral response to catumaxomab correlates with clinical outcome: results of the pivotal phase II/III study in patients with malignant ascites.

Syringe pump can be contr Breast cancer tissue arra Breast cancer tissue arra Cervical carcinoma tissue FDA Standard Frozen Tissu FDA Standard Frozen Tissu FDA Standard Frozen Tissu FDA Standard Frozen Tissu Multiple organ tumor tiss Malignant melanoma, metas Malignant melanoma, metas Malignant melanoma tissue

Related Pathways

paperclip


Notice: Trying to get property of non-object in /home/genpcr5/public_html/gentaurpub.com/result.php on line 218
#
Notice: Trying to get property of non-object in /home/genpcr5/public_html/gentaurpub.com/result.php on line 219

Notice: Trying to get property of non-object in /home/genpcr5/public_html/gentaurpub.com/result.php on line 219

Notice: Trying to get property of non-object in /home/genpcr5/public_html/gentaurpub.com/result.php on line 219

Notice: Trying to get property of non-object in /home/genpcr5/public_html/gentaurpub.com/result.php on line 219

Notice: Trying to get property of non-object in /home/genpcr5/public_html/gentaurpub.com/result.php on line 219

Notice: Trying to get property of non-object in /home/genpcr5/public_html/gentaurpub.com/result.php on line 219
   // Save this To Up

Notice: Trying to get property of non-object in /home/genpcr5/public_html/gentaurpub.com/result.php on line 243

Notice: Trying to get property of non-object in /home/genpcr5/public_html/gentaurpub.com/result.php on line 243


Notice: Trying to get property of non-object in /home/genpcr5/public_html/gentaurpub.com/result.php on line 244

Notice: Trying to get property of non-object in /home/genpcr5/public_html/gentaurpub.com/result.php on line 244

Notice: Trying to get property of non-object in /home/genpcr5/public_html/gentaurpub.com/result.php on line 244

Notice: Trying to get property of non-object in /home/genpcr5/public_html/gentaurpub.com/result.php on line 245

Notice: Trying to get property of non-object in /home/genpcr5/public_html/gentaurpub.com/result.php on line 245


Notice: Trying to get property of non-object in /home/genpcr5/public_html/gentaurpub.com/result.php on line 251

Notice: Trying to get property of non-object in /home/genpcr5/public_html/gentaurpub.com/result.php on line 251

Notice: Trying to get property of non-object in /home/genpcr5/public_html/gentaurpub.com/result.php on line 251

Notice: Trying to get property of non-object in /home/genpcr5/public_html/gentaurpub.com/result.php on line 251

Notice: Trying to get property of non-object in /home/genpcr5/public_html/gentaurpub.com/result.php on line 251

Notice: Trying to get property of non-object in /home/genpcr5/public_html/gentaurpub.com/result.php on line 251

2670 related Products with:


Notice: Trying to get property of non-object in /home/genpcr5/public_html/gentaurpub.com/result.php on line 255

Notice: Trying to get property of non-object in /home/genpcr5/public_html/gentaurpub.com/result.php on line 255
No related Items

Related Pathways

  •  
  • No related Items
paperclip

#19241870   // Save this To Up

[Intermediate filament proteins nestin and vimentin in the rat kidney cells].

The data on the presence of the kidney cells can contain neuroglial markers (nestin, vimentin, glial fibrillar acidic protein--GFAP) appeared unexpected and require a detailed investigation. Therefore, the purpose of the current study was to demonstrate the structures containing these proteins in the rat kidney by means of immunocytochemistry. Immunocytochemical staining was performed using the antimouse monoclonal and antirabbit polyclonal antibodies. It was demonstrated that the renal corpuscle contained both nestin- and vimentin-immunopositive cells (podocytes). Vimentin was also detected in the cells of parietal epithelium of the glomerular capsule, single cells of proximal and distal tubular epithelium, medullar tubular structures, and in the stromal cells. No GFAP-positive cells were detected in the kidney. Thus, the combination of nestin and vimentin was found to be typical for adult rat kidney podocytes. This suggests probable similarity of cytophysiological properties of podocytes and activated CNS astrocytes.

2372 related Products with: [Intermediate filament proteins nestin and vimentin in the rat kidney cells].

GLP 1 ELISA Kit, Rat Gluc GLP 2 ELISA Kit, Rat Prog Glucagon ELISA KIT, Rat G Leptin ELISA Kit, Rat Lep Rat Anti-Mouse Dendritic Octyl â D 1 thioglucopyr Sterile filtered rat ser anti HSV (II) gB IgG1 (mo anti HCMV IE pp65 IgG1 (m anti HCMV gB IgG1 (monocl Insulin 1 (Rat), syntheti Goat Anti-Rat MARCH10, (i

Related Pathways

paperclip

#17997516   // Save this To Up

Monoclonal antibody selection for interleukin-4 quantification using suspension arrays and forward-phase protein microarrays.

A recombinant mouse interleukin-4 (IL-4) and three different purified rat antimouse IL-4 monoclonal antibodies (Mab) with different clonalities were employed as a model system. This system was used to examine monoclonal antibody effectiveness using both conventional and high-throughput measurement techniques to select antibodies for attaining the most sensitive detection of the recombinant IL-4 through the "sandwich-type" immunoassays. Surface plasmon resonance (SPR) measurements and two high-throughput methods, suspension arrays (also called multiplexed bead arrays) and forward-phase protein microarrays, predicted the same capture (BVD4-1D11) and detection (BVD6-24G2) antibody pair for the most sensitive detection of the recombinant cytokine. By using this antibody pair, we were able to detect as low as 2 pg/mL of IL-4 in buffer solution and 13.5 pg/mL of IL-4 spiked in 100% normal mouse serum with the multiplexed bead arrays. Due to the large amount of material required for SPR measurements, the study suggests that the multiplexed bead arrays and protein microarrays are both suited for the selection of numerous antibodies against the same analyte of interest to meet the need in the areas of systems biology and reproducible clinical diagnostics for better patient care.

2622 related Products with: Monoclonal antibody selection for interleukin-4 quantification using suspension arrays and forward-phase protein microarrays.

Anti C Reactive Protein A Mouse Anti-F1 protein (YE Mouse Monoclonal Antibody MOUSE ANTI BOVINE ROTAVIR ReadiLink™ mFluor™ Vi ReadiLink™ mFluor™ Vi ReadiLink™ mFluor™ Vi MOUSE ANTI BORRELIA BURGD G protein-coupled recepto Anti CEL Monoclonal Antib Anti AGE 3 Monoclonal Ant anti GFP antibody, rat mo

Related Pathways

paperclip

#17805113   // Save this To Up

A novel in vivo model of human hemangioma: xenograft of human hemangioma tissue on nude mice.

Experimental models of human infantile hemangiomas are needed, although none of the current ones is ideal in representing the natural development of hemangioma. In this article, the authors present a nude mice model of human hemangioma with serial morphologic findings on grafts.

1701 related Products with: A novel in vivo model of human hemangioma: xenograft of human hemangioma tissue on nude mice.

Human normal bone and ost Human breast invasive duc Human breast invasive duc ELISA kit CLGI,Collagenas Goat Anti-Human Tissue Fa Multiple organ tumor tiss Multiple organ tumor tiss Multiple organ tumor tiss Frozen multiple human org Anti C Reactive Protein A Anti AGO2 Human, Monoclon Anti AGO2 Human, Monoclon

Related Pathways

paperclip

#17032310   // Save this To Up

Anti-tumor effect in an in vivo model by human-derived pancreatic RNase with basic fibroblast growth factor insertional fusion protein through antiangiogenic properties.

It is thought that the export of angiogenic fibroblast growth factors (FGF) from tumors may be involved in the onset of tumor angiogenesis. To create a new active targeting drug that inhibits the tumor angiogenic process without toxicities to normal cells, human basic FGF (h-bFGF) was inserted genetically into the Gly89 position of cross-linked RNase1 (the ribonuclease inhibitor protein [RI] binding site of cross-linked human pancreatic RNase) to prevent stereospecific binding to RI. The resultant insertional-fusion protein (CL-RFN89) was active both as h-bFGF and as RNase1. Furthermore, it acquired an additional ability of evading RI through steric blockade of RI binding caused by the fused h-bFGF domain. In the present study, the effect of the resultant protein, CL-RFN89, on the antitumor response though its antiangiogenic properties was investigated in an in vivo model. Continuous systemic treatment with CL-RFN89 significantly inhibited the growth of human A431 squamous cell carcinomas in vivo. Seven days of treatment with CL-RFN89 resulted in a 58.2% inhibition of tumor growth compared with control mice (P < 0.0001). Furthermore, immunohistochemistry using a rat antimouse CD31 antibody showed that treatment with CL-RFN89 reduced tumor vascularization. These findings identify CL-RFN89 as a potent systemic inhibitor of tumor growth as a result of its antiangiogenic properties. This protein appears to be a new systemic antitumor agent.

1617 related Products with: Anti-tumor effect in an in vivo model by human-derived pancreatic RNase with basic fibroblast growth factor insertional fusion protein through antiangiogenic properties.

Goat Anti-Human Fibroblas Rat monoclonal anti mouse Rat monoclonal anti mouse Rat monoclonal anti mouse Rat monoclonal anti mouse Rat monoclonal anti mouse Growth Factor (Human) Ant Rabbit Anti-APIP Apaf1 In Rabbit Anti-APIP Apaf1 In Rabbit Anti-TNIP2 ABIN2 T Rabbit Anti-TNIP2 ABIN2 T Rabbit Anti-Cell death in

Related Pathways

paperclip

#16858292   // Save this To Up

Long-term survival of xenogeneic heart grafts achieved by costimulatory blockade and transient mixed chimerism.

Xenotransplantation holds great promise in clinical medicine, but is limited by the vigorous rejection response elicited against solid organs transplanted across species barriers. In this study, we investigated the role of anti-CD40L monoclonal antibody (mAb) in inducing xenogeneic mixed chimerism and donor-specific heart transplantation tolerance.

1659 related Products with: Long-term survival of xenogeneic heart grafts achieved by costimulatory blockade and transient mixed chimerism.

Goat Anti-Human Androgen 1,1'-Dioctadecyl-3,3,3',3 Interleukin-34 IL34 (N-t HMGB1 (N-term) antibody DGKE (N term) HLTV I envelope recombina 5(6) FAM [5 (and 6) Carbo 5(6) FAM, SE [5 (and 6) C Androgen Receptor (Phosph Androgen Receptor (Phosph Goat Anti-Human XPNPEP1, Goat Anti-Human UXT, (C T

Related Pathways

paperclip

#16511791   // Save this To Up

Flow cytometric patterns in blood from dogs with non-neoplastic and neoplastic hematologic diseases using double labeling for CD18 and CD45.

In dogs, flow cytometry is used in the phenotyping of immunologic cells and in the diagnosis of hemic neoplasia. However, the paucity of specific antibodies for myeloid cells and B lymphocytes and of labeled antibodies for multicolor techniques limits the ability to detect all leukocyte subpopulations. This is especially true for neoplastic and precursor cells. CD18 and CD45 are expressed on all leukocytes and are involved in cell activation, and together could be useful in helping determine cell lineage.

1616 related Products with: Flow cytometric patterns in blood from dogs with non-neoplastic and neoplastic hematologic diseases using double labeling for CD18 and CD45.

Androgen Receptor (Phosph Androgen Receptor (Phosph Rabbit Anti-Human Androge Rabbit Anti-Human Androge anti H inh human blood an HBeAg test strip, Infecti Anti-HBeAg (HBeAb) test s Anti-HBcAg (HBcAb) test s HBV-5 panel test, sAg sAb HCV antibody test strip, HBV-3 panel test, HBsAg H HIV Self Test Kit, 1Test

Related Pathways

paperclip

#14676108   // Save this To Up

Neutrophils contribute to the biological antitumor activity of rituximab in a non-Hodgkin's lymphoma severe combined immunodeficiency mouse model.

Rituximab is a chimeric antibody (Ab) directed against the cluster designated (CD) 20 antigen found on normal and malignant B cells. Rituximab activity has been associated with complement-mediated cytotoxicity, Ab-dependent cellular cytotoxicity (ADCC), and induction of apoptosis. Recent studies performed in severe combined immunodeficiency (SCID) mouse models suggest that in vivo rituximab-associated ADCC is mediated via the FcgammaRIII receptor on effector cells. Despite low level expression of FcgammaRIII, neutrophils are also known to induce ADCC primarily via FcgammaRI receptor (CD64). The purpose of this work was to study the effect(s) of neutrophils on the in vivo antitumor activity of rituximab.

2867 related Products with: Neutrophils contribute to the biological antitumor activity of rituximab in a non-Hodgkin's lymphoma severe combined immunodeficiency mouse model.

FDA Standard Frozen Tissu FDA Standard Frozen Tissu FDA Standard Frozen Tissu FDA Standard Frozen Tissu Anti AGO2 Mouse, Monoclon Anti AGO2 Mouse, Monoclon Shiga Toxin 1 antibody, M Shiga Toxin 2 antibody, M Goat Anti-Mouse SAR1, (in RANK Ligand Soluble, Huma RANK Ligand Soluble, Huma Integrin β1 (CD29) Antib

Related Pathways