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Search results for: Mouse pre-microRNA Expression Construct mir-17+18a+19a+20a+19b-1+92a-1

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#33134908   2020/09/06 To Up

Hepatic miR-192-3p reactivation alleviates steatosis by targeting glucocorticoid receptor.

The paradox of hepatic insulin resistance describes the inability for liver to respond to bioenergetics hormones in suppressing gluconeogenesis whilst maintaining lipid synthesis. Here, we report the deficiency of miR-192-3p in the livers of mice with diabetes and its role in alleviating hepatic steatosis.
Zhangting Wang, Kai-Kei Miu, Xueyan Zhang, Angel Tsz-Yau Wan, Gang Lu, Hoi-Hung Cheung, Heung-Man Lee, Alice Pik-Shan Kong, Juliana Chung-Ngor Chan, Wai-Yee Chan

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