Gentaur Pub

#27144935   2016/05/04 To Up

Association of Hypoalbuminemia With Osteoporosis: Analysis of the National Health and Nutrition Examination Survey.

The association of hypoalbuminemia with osteoporosis in human studies is controversial.
Farsad Afshinnia, Subramaniam Pennathur

1835 related Products with: Association of Hypoalbuminemia With Osteoporosis: Analysis of the National Health and Nutrition Examination Survey.

5 G100ul1 module1 module50 mg1 15 ml 3 modules

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#25366362   2015/02/10 To Up

Experience with molecular adsorbent recirculating system treatment in 20 children listed for high-urgency liver transplantation.

For more than 10 years, children at our national center for pediatric liver transplantation (LT) have been treated with Molecular Adsorbent Recirculating System (MARS) liver dialysis as a bridging therapy to high-urgency LT. Treatment was reserved for 20 patients with the highest degrees of hepatic encephalopathy (HE; median grade = 3.5). Death from neurological sequelae was considered imminent for these patients, and this was further reflected in significantly higher international normalized ratios and ammonia levels and worse prognostic liver indices (Model for End-Stage Liver Disease/Pediatric End-Stage Liver Disease scores and liver injury units) in comparison with 32 wait-listed patients who did not receive MARS dialysis. MARS therapy was generally well tolerated, with a reduction in thrombocytes and hemorrhaging as the most common side effects. HE improvement was documented in 30% of the treated patients, but progression to grade IV encephalopathy occurred in 45% of the patients despite the treatment. Serum ammonia, bilirubin, bile acid, and creatinine levels significantly decreased during treatment. Eighty percent of MARS-treated patients survived to undergo LT, and their survival was equivalent to that of non-MARS-treated patients with severe liver failure (69%, P = 0.52). The heterogeneity between MARS-treated patients and non-MARS-treated patients in our cohort precluded a statistical evaluation of a benefit from MARS for patient survival. Our data demonstrate the safety of MARS even in the most severely ill patients awaiting LT, but strategies that promote the more rapid and widespread availability of high-quality donor organs remain of critical importance for improving patient survival in cases of severe acute liver failure.
Willem S Lexmond, Carin M L Van Dael, René Scheenstra, Joanne F Goorhuis, Egbert Sieders, Henkjan J Verkade, Patrick F Van Rheenen, Martin Kömhoff

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200ul20000 Units200ul 6 ml Ready-to-use 5mg2000 Units

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#7798165   // To Up

Manual plasmapheresis in the treatment of Guillain-Barré syndrome.

We report on 41 patients with Guillain-Barré Syndrome (GBS) with disability grade 4 and 5 who were treated with manual plasma exchange (PE). Approximately 20-40 ml/kg body weight of plasma was removed with each manual PE; 63% of patients needed one PE, 24% needed two, 10% needed three, and 2% needed four plasma exchanges. Normal saline, human serum albumin (NSA) and fresh frozen plasma were used in varying proportions as replacement solutions. Ninety-one percent of the patients resumed walking with very little assistance ranging from 4 to 56 days with an average of 25 days from the commencement of the first PE. Manual PE in our series was effective and safe as the reported experience of automated apheresis and less volume of plasma was exchanged in our patients undergoing manual PE when compared to those treated in other studies employing automated PE.
N S de Zoysa, K K Jayaweera, T Vaithianathan

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1100 μg100 assays

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