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Search results for: Dansylaminophenylboronic acid, Fluorescent Reagent, 50mg

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#25960433   2015/03/18 To Up

Fusion of hIgG1-Fc to 111In-anti-amyloid single domain antibody fragment VHH-pa2H prolongs blood residential time in APP/PS1 mice but does not increase brain uptake.

Llama single domain antibody fragments (VHH), which can pass endothelial barriers, are being investigated for targeting amyloid plaque load in Alzheimer's disease (AD). Contrary to conventional human or murine antibodies consisting of IgG or F(ab')2 antibody fragments, VHH are able to effectively pass the blood brain barrier (BBB) in vitro. However, in earlier in vivo studies, anti-amyloid VHH showed poor BBB passage due to their short serum half-lives. It would be of interest to develop a VHH based protein with elongated serum half-life to enhance BBB passage, allowing the VHH to more easily reach the cerebral amyloid deposits.
Maarten Rotman, Mick M Welling, Marlinde L van den Boogaard, Laure Grand Moursel, Linda M van der Graaf, Mark A van Buchem, Silvère M van der Maarel, Louise van der Weerd

2321 related Products with: Fusion of hIgG1-Fc to 111In-anti-amyloid single domain antibody fragment VHH-pa2H prolongs blood residential time in APP/PS1 mice but does not increase brain uptake.

50 UG100ug100μg100ul 100 UG100μg100ug Lyophilized100ug Lyophilized100ug Lyophilized100ug

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#25544189   2014/12/09 To Up

Extractive liquid-liquid spectrofluorometric determination of trace and ultra concentrations of bromate in water samples by the fluorescence quenching of tetraphenylphosphonium iodide.

A low cost and selective spectrofluorimetric method has been developed for trace determination of bromate ions in water. The method has been based upon complete extraction of the produced yellow colored ion associate of the reagent tetraphenylphosphonium iodide (TPP(+) I(-)) and bromate ions from aqueous media into chloroform and measuring the fluorescence quenching at λex/em=242/305nm. The composition, stability and the most probable mechanism of the produced associate have been determined. The plot of fluorescence intensity of TPP(+) I(-)vs. bromate concentration was linear in the range 0.86-150.0μgL(-1). The limits of detection (LOD) and quantification (LOQ) of BrO3(-) were 0.24 and 0.76μgL(-1), respectively. The method was found free from most of the interferences present in chromatographic, spectrofluorometric and spectrophotometric methods. Intra and inter-day laboratory accuracy and precision for analysis of bromate in water were determined. The method provides better performance compared to the international standard method recently issued (ISO 11206:2011). The method was applied satisfactorily for analysis of 1.0μgL(-1) bromate in the presence of high excess of chloride (50mg/L) without pretreatment with a relative standard deviation (RSD) of ±2.9%. The method was applied for analysis of bromate in various water samples. Statistical comparison of the results of the proposed method with those obtained by the standard method revealed no significant differences in the accuracy and precision.
H M Al-Saidi, M S El-Shahawi

2586 related Products with: Extractive liquid-liquid spectrofluorometric determination of trace and ultra concentrations of bromate in water samples by the fluorescence quenching of tetraphenylphosphonium iodide.

20 100 100 20 20 20 20 20 20 100 1 ml100

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#20864088   2010/09/22 To Up

The antimicrobial efficacy of Fructus mume extract on orthodontic bracket: a monospecies-biofilm model study in vitro.

the aim of this study was to evaluate the antimicrobial efficacy of Traditional Chinese Medicine Fructus mume on a monospecies-biofilm model established on orthodontic brackets in vitro.
Yong Chen, Ricky W K Wong, C J Seneviratne, Urban Hägg, Colman McGrath, L P Samaranayake, Richard Kao

2075 related Products with: The antimicrobial efficacy of Fructus mume extract on orthodontic bracket: a monospecies-biofilm model study in vitro.

100ug18 kgs196 tests

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