Anti-ICAM1, Rat Monoclonal to ICAM1, Isotype IgG2b, Host Rat productsSearch results for: Anti-ICAM1, Rat Monoclonal to ICAM1, Isotype IgG2b, Host Rat
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Anti-LFA-1 alpha reduces the dose of cyclosporin A needed to produce immunosuppression in heterotopic cardiac transplanted rats.
Monoclonal antibodies (MAb) against cell adhesion molecules prolong the time to acute rejection of transplanted organs in animals. Postulated mechanisms of action include blockade of trafficking of host leukocytes into or recognizing of effector/target cells within the allograft. We examined whether an anti-ICAM-1 (1A29), anti-LFA-1 alpha (WT.1), or anti-CD-18 (WT.3) could reduce the immunosuppressive dose of cyclosporin A (CsA) when used in combination.P C Harrison, J B Madwed
