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Coming of Age With Cancer: Physical, Social, and Financial Barriers to Independence Among Emerging Adult Survivors
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To explore the transition to self-care among a sample of emerging adult cancer survivors after hematopoietic cell transplantation (HCT). 
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2675 related Products with: Coming of Age With Cancer: Physical, Social, and Financial Barriers to Independence Among Emerging Adult Survivors
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Biomarker potential of ST6GALNAC3 and ZNF660 promoter hypermethylation in prostate cancer tissue and liquid biopsies.

Current diagnostic and prognostic tools for prostate cancer (PC) are suboptimal, leading to overdiagnosis and overtreatment. Aberrant promoter hypermethylation of specific genes has been suggested as novel candidate biomarkers for PC that may improve diagnosis and prognosis. We here analyzed ST6GALNAC3 and ZNF660 promoter methylation in prostate tissues, and ST6GALNAC3, ZNF660, CCDC181, and HAPLN3 promoter methylation in liquid biopsies. First, using four independent patient sample sets, including a total of 110 non-malignant (NM) and 705 PC tissue samples, analyzed by methylation specific qPCR or methylation array, we found that hypermethylation of ST6GALNAC3 and ZNF660 was highly cancer-specific with areas under the curve (AUC) of receiver operated characteristic (ROC) curve analysis of 0.917-0.995 and 0.846-0.903, respectively. Furthermore, ZNF660 hypermethylation was significantly associated with biochemical recurrence in two radical prostatectomy (RP) cohorts of 158 and 392 patients, and remained significant also in the subsets of patients with Gleason score ≤7 (univariate Cox regression and log rank tests P<0.05), suggesting that ZNF660 methylation analysis can potentially help to stratify low/intermediate grade PCs into indolent vs. more aggressive subtypes. Notably, ZNF660, hypermethylation was also significantly associated with poor overall- and PC-specific survival in the RP cohort (n=158) with long clinical follow-up available. Moreover, as proof of principle, we successfully detected highly PC-specific hypermethylated circulating tumor DNA (ctDNA) for ST6GALNAC3, ZNF660, HAPLN3 and CCDC18 in liquid biopsies (serum) from 27 PC vs. 10 BPH patients, using droplet digital methylation-specific PCR analysis. Finally, we generated a three-gene (ST6GALNAC3/CCDC181/HAPLN3) ctDNA hypermethylation model, which detected PC with 100% specificity and 67% sensitivity. In conclusion, we here for the first time demonstrate diagnostic biomarker potential of ST6GALNAC3 and ZNF660 methylation, as well as prognostic biomarker potential of ZNF660. Furthermore, we show that hypermethylation of four genes can be detected in ctDNA in liquid biopsies (serum) from PC patients.

2832 related Products with: Biomarker potential of ST6GALNAC3 and ZNF660 promoter hypermethylation in prostate cancer tissue and liquid biopsies.

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Variability in Condom Use Trends by Sexual Risk Behaviors: Findings from the 2003-2015 National Youth Risk Behavior Surveys.

To examine variability in condom use trends by sexual risk behavior among US high school students.

2613 related Products with: Variability in Condom Use Trends by Sexual Risk Behaviors: Findings from the 2003-2015 National Youth Risk Behavior Surveys.

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The Etiology of Vaginal Discharge Syndrome in Zimbabwe Results from the Zimbabwe STI Etiology Study.

Symptomatic vaginal discharge is a common gynecological condition managed syndromically in most developing countries. In Zimbabwe, women presenting with symptomatic vaginal discharge are treated with empirical regimens that commonly cover both sexually transmitted infections (STI) and reproductive tract infections, typically including a combination of an intramuscular injection of kanamycin, and oral doxycycline and metronidazole regimens. This study was conducted to determine the current etiology of symptomatic vaginal discharge and assess adequacy of current syndromic management guidelines.

2024 related Products with: The Etiology of Vaginal Discharge Syndrome in Zimbabwe Results from the Zimbabwe STI Etiology Study.

Thermal Shaker with cooli FDA Standard Frozen Tissu FDA Standard Frozen Tissu FDA Standard Frozen Tissu FDA Standard Frozen Tissu FDA Standard Frozen Tissu FDA Standard Frozen Tissu Multiple organ tumor tiss MultiGene Gradient therm BACTERIOLOGY BACTEROIDES Macrophage Colony Stimula Macrophage Colony Stimula

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Sexually Transmitted Infection Prevalence among Homeless Adults in the U.S.: A Systematic Literature Review.

Homelessness significantly affects health and well-being. Homeless adults often experience co-occurring and debilitating physical, psychological, and social conditions. These determinants are associated with disproportionate rates of infectious disease among homeless adults, including tuberculosis, HIV, and hepatitis. Less is known about sexually transmitted infection (STI) prevalence among homeless adults.

1830 related Products with: Sexually Transmitted Infection Prevalence among Homeless Adults in the U.S.: A Systematic Literature Review.

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State laws related to billing third parties for healthcare services at public STD clinics in the United States.

Health departments (HDs) cite state laws as barriers to billing third parties for sexually transmitted disease (STD) services, but the association between legal/policy barriers and third party HD billing has not been examined. This study investigates the relationship between laws that may limit HDs' ability to bill, clinic perceptions of billing barriers, and billing practices.

2547 related Products with: State laws related to billing third parties for healthcare services at public STD clinics in the United States.

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Prescription of Pre-Exposure Prophylaxis to MSM Diagnosed and Reported with Gonorrhea, STD Surveillance Network, 2016.

Using a representative sample of gonorrhea cases in select jurisdictions, we estimated the proportion of eligible men who have sex with men (MSM) reporting being prescribed pre-exposure prophylaxis (PrEP) to prevent HIV infection. In 2016, half (51.3%) of the estimated 33,165 eligible MSM reported being prescribed PrEP by their healthcare provider.

1918 related Products with: Prescription of Pre-Exposure Prophylaxis to MSM Diagnosed and Reported with Gonorrhea, STD Surveillance Network, 2016.

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[Level of knowledge of Quality Commitment Campaign (QCC) and of "do not do" recommendations amongst GPs, pediatricians and nurses Primary Care].

To evaluate if the Quality Commitment Campaign (QCC) was sufficiently known among primary care professionals (PC), and second, to evaluate the knowledge about certain recommendations of what should not be done in PC.

1077 related Products with: [Level of knowledge of Quality Commitment Campaign (QCC) and of "do not do" recommendations amongst GPs, pediatricians and nurses Primary Care].

Ofloxacin CAS Number [824 Androgen Receptor (Phosph Androgen Receptor (Phosph Rabbit Anti-Human Androge Rabbit Anti-Human Androge Androgen Receptor (Ab 650 Primary antibody DOK1 An AZD-3514 Mechanisms: Andr 17β-Acetoxy-2α-bromo-5 (5α,16β)-N-Acetyl-16-[2 (5α,16β)-N-Acetyl-16-ac 5α-N-Acetyl-2'H-androst-

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Effects of a prevention program for internet addiction among middle school students in South Korea.

This study explored the effects of a self-regulatory efficacy improvement program on self-control, self-efficacy, internet addiction, and time spent on the internet among middle school students in South Korea. The program was led by school nurses, and it is integrated self-efficacy and self-regulation promotion strategies based on Bandura's social cognitive theory.

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Tactile Feedback can be Used to Redistribute Flexion Motion Across Spine Motion Segments.

This experiment investigates the efficacy of tactile feedback in affecting changes to dynamic spine movements. A sample of (n = 24) young, healthy males were assessed while completing targeted spine flexion movements with instruction to minimize stretching of the skin beneath an applied tactile stimulus (liquid bandage). Localized tactile stimuli were placed bilaterally at either lumbar (L4), lower thoracic (T10) or upper thoracic (T4) levels. Results demonstrate that localized tactile feedback elicited a re-distribution of spine flexion movement across spine sub-sections (e.g. lumbar vs. thoracic) and intervertebral segments (e.g. C7/T1 through L5/S1). Further, tactile feedback successfully limited the magnitude of end-range flexion, but did not limit functional mid-range spine flexion. Finally, tactile feedback located in the lower thoracic region (T10) increased thoracic flexion variability; however, tactile feedback located at the T4 and L4 regions had no significant effect on movement variability. These findings provide evidence that spine neuromuscular control patterns can be altered using simple tactile stimuli. In terms of low back injury prevention and/or rehabilitation, the tactile feedback investigated here has apparent utility in limiting recognized mechanical risk factors for low back injury; specifically, the local incidence of flexion at specific spine levels, and the incidence of end-range flexion.

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N,N,N Trimethyl 4 (6 phen D-Alanine Benzyl Ester p- L-Alanine Benzyl Ester p- (2S)-2-Amino-benzenebutan 1,5-Anhydro-4,6-O-benzyli 1,5-Anhydro-4,6-O-benzyli (1R,3S,5R)-2-Azabicyclo[3 4,6-O-Benzylidene-N-(tert 3-O-Benzyl-4-O-methyl Tol 6-(Benzyloxy)-α-chloro-m 4-(Benzyloxy)-3-hydroxybe 4-(Benzyloxy)-3-hydroxybe

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